استادیار دکتر آنژیلا عطایی

دکتر آنژیلا عطایی پیرکوه استادیار ویروس شناسی و رییس دپارتمان پاپیلوما در مرکز تحقیقات ویروس شناسی بالینی دانشگاه علوم پزشکی تهران است. دکتر عطایی مدارک کارشناسی ارشد و دکترای تخصصی ویروس شناسی را از  دانشگاه‌ها ی علوم پزشکی ایران و علوم پزشکی تهران اخذ کرده است و هم اکنون علاوه بر فعالیت در دانشگاه‌های علوم پزشکی ایران و تهران به عنوان عضو کنسرسیوم دانشگاهی مقابله با کووید 19 با شبکه تحقیقات بیماری‌های ویروسی وزارت بهداشت، درمان و آموزش پزشکی همکاری می کند.

Angila Ataei-Pirkooh

Ataei.a@iums.ac.ir

anjilaataei@gmail.com

Career Summary

2012- present    Assistant professor, Iran University of Medical Sciences, Tehran, Iran

2003-2012         Virology laboratory scientist, Iran University of Medical Sciences, Tehran, Iran

1995-2003         Medical laboratory technologist, Ghazvin University of Medical Sciences, Ghazvin, Iran

Education

-Mazandaran University of Medical Sciences, Sari, Iran

Bachelor of Science in laboratory Medicine, 2000

-Iran University of Medical Sciences, Tehran, Iran

Master in Medical Virology, 2002

-Tehran University of Medical Sciences, Tehran, Iran

Ph.D. in Medical Virology, 2008

Iran University of Medical Sciences, Tehran, Iran

• Master in Medical Education, 2016

Publications

1. Investigation of CTNNB1 gene mutations and expression in hepatocellular carcinoma and cirrhosis in association with hepatitis B virus infection. Infectious Agents and Cancer. 2020.  DOI: https://doi.org/10.1186/s13027-020-00297-5
2. Inhibition of H1N1 influenza virus infection by zinc oxide nanoparticles: another emerging application of nanomedicine. Journal of Biomedical Science. 2019. DOI: https://doi.org/10.1186/s12929-019-0563-4
3. Assessment of airborne enteric viruses emitted from wastewater treatment plant: Atmospheric dispersion model, quantitative microbial risk assessment, disease burden. Environmental Pollution. 2019. https://doi.org/10.1016/j.envpol.2019.07.010
4. Presence and diversity of Leishmania RNA virus in an old zoonotic cutaneous leishmaniasis focus, northeastern Iran: haplotype and phylogenetic based approach. International Journal of Infectious Diseases. 2020. https://doi.org/10.1016/j.ijid.2020.08.033
5. HIV-1 integrase drug-resistance mutations in Iranian treatment-experienced HIV-1-infected patients. Archives of Virology. 2020.  DOI: https://doi.org/10.1007/s00705-019-04463-y
6. Human Reoviruses Serotype 3 Effectively Target Huh-7 Cells. Iranian Journal of Virology. 2020;14(2): 23-28
7. Molecular epidemiology of epstein-barr virus (ebv) in patients with hematologic malignancies. Asian Pacific journal of cancer prevention: APJCP. 2020. doi: 10.31557/APJCP.2020.21.3.693
8. The Frequency of HIV-1 Infection in Iranian Children and Determination of the Transmitted Drug Resistance in Treatment-Naïve Children. Current HIV Research. 2019. DOI: https://doi.org/10.2174/1570162X17666191106111211
9. The Human Cathelicidin LL-37, a Defensive Peptide Against Rotavirus Infection. International Journal of Peptide Research and Therapeutics. 2019. DOI: https://doi.org/10.1007/s10989-019-09896-2
10. Purification of human reovirus in Monolayers of L-929 cells. Iran Journal of Virology. 2019, 13(1): 35-40
11. Evaluating the Antiviral Activities of Human Cathelicidin LL-37 Peptide Against Rotavirus in Vitro. The Journal ofQazvin University of Medical Sciences (JQUMS. 2019. https://doi.org/10.32598/JQUMS.23.3.214
12. Molecular diagnosis of occult hepatitis C virus infection in Iranian injection drug users. Archives of virology. 2019. https://doi.org/10.1007/s00705-018-4066-5
13. Rotavirus Infection Enhances Levels of Autoantibodies Against Islet Cell Antigens GAD65 and IA-2 in Children with Type 1 Diabetes. Fetal and Pediatric Pathology . 2019. https://doi.org/10.1080/15513815.2018.1547338
14. Current antiretroviral drugs for human immunodeficiency virus infection: review article.   Tehran Univ Med J. 2019, 77(5): 273-281
15. Detection of HBV genome in the plasma and peripheral blood mononuclear cells of Iranian HBsAg negative patients with HIV infection: occult HBV infection. Archives of virology. 2018. https://doi.org/10.1007/s00705-018-3740-y 
16. Polyethylene glycol-coated zinc oxide nanoparticle: an efficient nanoweapon to fight against herpes simplex virus type 1. Nanomedicine. 2018. https://doi.org/10.2217/nnm-2018-0089
17. Center manifold analysis and Hopf bifurcation of within-host virus model. Computational Methods for differential Equations 2018, 6(3):266-279
18. Antiviral effects of Lactobacillus crispatus against HSV-2 in mammalian cell lines. Journal of the Chinese Medical Association  2018, 81(3):262-267
19. Investigation of viral infection in idiopathic pulmonary fibrosis among Iranian patients in Tehran. Microbial pathogenesis. 2017. https://doi.org/10.1016/j.micpath.2017.01.030
20. Detection and molecular identification of leishmania RNA virus (LRV) in Iranian Leishmania species. Archives of virology. 2016. DOI 10.1007/s00705-016-3044-z
21. Comparison of three different methods for detection of IL28 rs12979860 polymorphisms as a predictor of treatment outcome in patients with hepatitis C virus. Osong Public Health and Research Perspectives. 2016. https://doi.org/10.1016/j.phrp.2015.11.004
22. In vitro adherence of Lactobacillus strains isolated from the vaginas of healthy Iranian women. Journal of the Chinese Medical Association (2016) 1-7
23. Serostatus of Epstein-Barr virus in Iranian MS Patients. Acta Neurol Belg 2016: 116: 43-46
24. Assessment of humoral immune response of a Cytomegalovirus DNA-vaccine candidate in BALB/c mice. Vaccine Research 2015, 2(3): 33-37
25. Human Bocavirus in Hospitalized Iranian Adults with Respiratory Tract Infections during January-June 2014. Journal of Pure and Applied Microbiology 2015: 1-6
26. Sero-prevalence of Herpes Simplex and Epstein Barr Viruses in HIV positive patients in Tehran. Iranian Journal of Virology 2015;9(4): 29-34
27. Middle East Respiratory Syndrome Coronavirus(MERS-CoV): A Review Article.Iranian Journal of Virology 2014, (2,3): 59-68
28. Evaluation of the Role of Herpes Simplex Virus Type 1 in the Secretion of Interleukin-1β (IL-1β) by Cultured Gingival Epithelial Cells.Iranian Journal of Virology 2014,8(4): 1-5
29. Respiratory Syncytial Virus Infection In Children Referred To Kasra Hospital In Tehran During The Period Of 2012-2014. Iranian Journal of Virology 2014, 8(2,3): 55-8 
30. . Distribution of Hepatitis B Virus Genotypes in Azerbaijani Patients With Chronic Hepatitis B Infection. Hepatitis Monthly 2014, 14(12):1-5
31. The inhibitory effect of Acyclovir loaded nano-niosomes against herpes simplex virus type-1 in cell culture. Medical Journal of the Islamic Republic of Iran 2014, 28(99):1-5
32. Reovirus Inhibits Poliovirus Replication upon Superinfection.Intervirology, 2012;55:62–67
33. Accurance of Respiratory Syncytial Virus Infection in Children Referred to Kasra Hospital Diagnostic Laboratory during 2009-2011. Iranian Journal of Virology 2011;5(1): 6-9
34. Incidence of Coinfection between Rotavirus and Some Enteropathogenic agents in Children Referred to Children Medical Center Hospital, Tehran, 2009. Iranian Journal of Virology 2011;5(1): 23-27
35. Evaluation of Immune Status to Measles in Vaccinated Population in Tehran, by Enzyme-linked Immunosorbent Assay and the Hemagglutination Inhibition Techniques (1386-1387). Iranaian  Journal of Virology 2010, 4(3 and 4): 43-46
36. Poliovirus particles do not form in preinfected cells with reovirus .Iranian Journal of Virology,2009,3:23
37. Peganum harmala seed extract can prevent HSV-1 replication in vitro. Iranian Journal of virology.2008,4:11-16
38. Development of a latex agglutination method for diagnosis of rotavirus infection. Iranian Journal of Medical Sciences.2007, 32(2):100-104
39. Evaluation of immune status to measles in vaccinated population in Tehran, using enzyme-linked immunosorbent assay and the hemagglutination inhibition techniques. Iranian Journal of virology .2007,1(4):27-30
40. Incidence of adenoviral conjunctivitis in  patients   Referred to the Iran University Affiliated Hospital . Iranian Journal of virology.2009, 3:7-11

Patents:

Development and evaluating the process of detecting Leishmania virus-infected parasite (LRV) based on indirect immunofluorescence (IFA) technique.  Iran property and deeds registration organization. 2020

 Paper presentation and lectures (congresses and workshops):

1. Inhibitory effect of Mellisa officinalis on herpes virus growth and multiplication. 16^th world society of cardio-thoracic surgeons. August 17-20, 2006. Ottawa. Canada
2. Incidence of coinfection between rotavirus and some enteropathogenic agents in children referred to children medical center hospital, Tehran, 2209, 4^th congress of laboratory and clinic.2011
3. Rhabdoviridae and Human. 1^st International World Rabies Day Seminar, 2014, Tehran
4. Study of inhibitory effect of Mentha Piperta and Caellia Sinensis extracts on the rotavirus replication using cell culture. 8^th International congress of laboratory and clinic, 2015, Tehran.
5. Effect of green tea extract on rotavirus infection in cultured cell. The 16^th International Iranian Congress of Microbiology, 2015, Tehran
6. Distribution of hepatitis B virus genotypes iv Azerbaijani hepatitis B chronic infected patients. 7^th International congress of laboratory and clinic, 2014. Tehran.
7. Mathematical Virology, Iranian Society for Virology, 2011
8. The first report of leishmania RNA virus2-1 in Iran using RT-PCR. 2nd International and 9th National Congress of Parasitology and Parasitic Diseases of Iran, Gilan, Iran;20-22 May 2015
9. New technologies: An effective approach to interactive e-learning in the medical sciences. The 8th National Conference of E-Learning in Medical Education. Feb 2-4, 2016. Tehran
10. Estimation of nonlinear dynamic system parameters, application in biological mathematics. 47^th Annual Iranian Mathematics Conference. 28-31 August 2014. Karaj. Iran
11. Assessing the educational needs of the doctoral course in medical virology using the Delphi technique. The 19th National Health Professions Education Conference and the 11th Shahid Motahari Educational Festival, 2018. Tehran
12. Ozone explodes SARS-CoV2, The University,s Exceptional Talent Office, 2020
13. Covid 19 and its identification methods. The University,s Exceptional Talent Office, 2020
14. Zoonotic Newemergent Viruses in Aquatic Animals. 4th International Congress of Fisherie sand Aquatic Research November18-20,2020 Tehran-Iran

14. Zoonotic Newemergent Viruses in Aquatic Animals. 4th International Congress of Fisherie sand Aquatic Research November18-20,2020 Tehran-Iran

Research Interests and Highlights:

Antiviral drugs and vaccines, Diabetogenic Viruses, Viruses and obesity , Double-stranded RNA containing viruses(Reoviridae, LRV,…), Enteric Viruses, Virus detection in urban sewage systems and sewage treatment plants, Papillomavirus , Cell culture techniques and virus isolation, Electron microscopy techniques in virology, Molecular detection of viruses, Nanotechnology, Mathematical virology. Medical Education (Needs assessment and curriculum development)

Professional Experiences

Animal and Insect cell culture and virus isolation, Molecular detection of Viruses, RNA and Protein Electrophoresis (PAGE, SDS-PAGE, Western Blotting), Immunofluorescence, Electron Microscopy, Medical laboratory 

Administrative experiences

Head of the Exceptional Talent Office, Iran University of Medical Sciences, Since 2011-2018

Supervisor of scientific Olympiads of medical sciences in Iran University of Medical Sciences, Since 2006 up to now  

Professional experiences

Member of the editorial board of Iranian Journal of Virology

Member of Scientific Committee, 4th International Congress of Fisheries and Aquatic Research November18-20,2020 Tehran-Iran

Member of Scientific Committee, The 8th National Conference of E-Learning in Medical Education. Feb 2-4, 2016. Tehran

Member of the Scientific Committee for the development of the Medical Virology Curriculum, Ministry of Health and Medical Education, 2015-2016 

Teaching

Advanced Virology for Ph.D. students of Medical Virology

Systematic Virology for Ph.D. students of Medical Virology 

General Virology for M.Sc. students of Medical Virology

Electron Microscopy for Ph.D. students of Medical Virology

Medical Virology for students of Medicine and pharmacy  

 Practical Virology for Ph.D. students of Medical Virology

Professional affiliation 

 Department of Virology, Faculty of Medicine, Iran University of Medical Sciences

Language

Persian(native), English(fluent), German (Busy learning and completing)

Interests

Literature, philosophy, music, astronomy, sports