دکتر اعظم قاضی اسدی

دکتر اعظم قاضی اسدی

ایمیل

aghaziasadi@sina.tums.ac.ir

رتبه علمی

Scientific researcher

تحصیلات

PHD in Medical Virology

دستاورد ها و افتخارات

• 2007.Ranked sixth in Nationwide Entrance Examination administered annually by the Ministry of Health and Medical Education for master degree in medical virology applicants.
• 2013. Ranked tenth in Nationwide Entrance Examination administered annually by the Ministry of Health and Medical Education for PHD degree in medical virology applicants.

مقالات

1. Jafarpoor A, Jazayeri SM, Bokharaei‐Salim F, Ataei‐Pirkooh A, Ghaziasadi A, Soltani S, Sadeghi A, Marvi SS, Poortahmasebi V, Khorrami SM, Hasanzad M. VDR gene polymorphisms are associated with the increased susceptibility to COVID‐19 among iranian population: A case‐control study. International Journal of Immunogenetics.
2. Rezaee Azhar I, Yaghoobi M, Mossalaeie MM, Kollaee Darabi A, Nejadeh AH, Jamshidi M, Ahani A, Karkhane Mahmoodi M, Ghalichi L, Shabanzadeh A, Ataei-Pirkooh A. Prevalence of human papilloma virus (HPV) genotypes between outpatients males and females referred to seven laboratories in Tehran, Iran. Infectious Agents and Cancer. 2022 Dec;17(1):1-8.
3. Fattahi Z, Mohseni M, Jalalvand K, Aghakhani Moghadam F, Ghaziasadi A, Keshavarzi F, Yavarian J, Jafarpour A, Mortazavi SE, Ghodratpour F, Behravan H. SARS‐CoV‐2 outbreak in Iran: The dynamics of the epidemic and evidence on two independent introductions. Transboundary and emerging diseases. 2022 May;69(3):1375-86.
4. Poortahmasebi V, Nejati A, Abazari MF, Nasiri Toosi M, Ghaziasadi A, Mohammadzadeh N, Tavakoli A, Khamseh A, Momenifar N, Gholizadeh O, Norouzi M. Identifying Potential New Gene Expression-Based Biomarkers in the Peripheral Blood Mononuclear Cells of Hepatitis B-Related Hepatocellular Carcinoma. Canadian Journal of Gastroenterology and Hepatology. 2022 Feb 28;2022.
5. Sedighi I, Fahimzad A, Pak N, Khalili M, Shokrollahi MR, Heydari H, Movahedi Z, Dashti AS, Cheraghali F, Shamsizadeh A, Mirkarimi M. A multicenter retrospective study of clinical features, laboratory characteristics, and outcomes of 166 hospitalized children with coronavirus disease 2019 (COVID‐19): A preliminary report from Iranian Network for Research in Viral Diseases (INRVD). Pediatric Pulmonology. 2022 Feb;57(2):498-507.
6. Poortahmasebi V, Alavian SM, Ghaziasadi A, Azadi A, Toosi MN, Jazayeri SM. Detection and Quantification of Hepatitis B Virus Genomes in Peripheral Blood Mononuclear Cells of Chronic Hepatitis B Virus Infection, Cirrhosis, and Hepatocellular Carcinoma Patients. Hepatitis Monthly. 2021 Oct 31;21(10).
7. Fahimzad A, Sedighi I, Pak N, Khalili M, Farahmand M, Shokrollahi MR, Heydari H, Movahedi Z, Dashti AS, Cheraghali F, Shamsizadeh A. A comparative analysis of clinical characteristics and laboratory findings of covid-19 between intensive care unit and non-intensive care unit pediatric patients: A multicenter, retrospective, observational study from iranian network for research in viral diseases (inrvd).
8. Fattahi Z, Mohseni M, Beheshtian M, Jafarpour A, Jalalvand K, Keshavarzi F, Behravan H, Ghodratpour F, Ashrafi FZ, Kalhor M, Azad M. Disease waves of SARS-CoV-2 in Iran closely mirror global pandemic trends (preprint).
9. Fattahi Z, Mohseni M, Beheshtian M, Jafarpour A, Jalalvand K, Keshavarzi F, Behravan H, Ghodratpour F, Ashrafi FZ, Kalhor M, Azad M. Disease waves of SARS-CoV-2 in Iran closely mirror global pandemic trends. MedRxiv. 2021 Jan 1.
10. Sedighi I, Fahimzad A, Pak N, Khalili M, Shokrollahi MR, Heydari H, Movahedi Z, Dashti AS, Cheraghali F, Shamsizadeh A, Mirkarimi M. A Multi-Center Retrospective Study of Clinical features, Laboratory Characteristics, and Outcomes of 325 Hospitalized Children with Coronavirus Disease 2019 (COVID-19); A Preliminary Report from Iranian Network for Research in Viral Diseases (INRVD).
11. Fattahi Z, Mohseni M, Jalalvand K, Moghadam FA, Ghaziasadi A, Keshavarzi F, Yavarian J, Jafarpour A, elham Mortazavi S, Ghodratpour F, Behravan H. Two independent introductions of SARS-CoV-2 into the Iranian outbreak. medRxiv. 2020 Jan 1.
12. Ghaziasadi A, Fakhari Z, Aghcheli B, Poortahmasebi V, Farahmand M, Norouzi M, Ghalichi L, Soleimani A, Hedayat Yaghoobi M, Ravanshad M, Jazayeri SM. High prevalence of occult hepatitis B infection (OBI) among healthy children and their parents in Alborz province, Iran; Vertical OBI, myth or truth?. Liver International. 2020 Jan;40(1):92-100.
13. Poortahmasebi V, Ghaziasadi A, Jazayeri SM. Molecular Mechanisms Responsible for Occult Hepatitis B Virus Infection. GOVARESH. 2019 Jun 25;24(2):68-80.
14. Mozhgani SH, Malekpour SA, Norouzi M, Ramezani F, Rezaee SA, Poortahmasebi V, Sadeghi M, Alavian SM, Zarei-Ghobadi M, Ghaziasadi A, Karimzadeh H. Molecular evolution and phylodynamics of hepatitis B virus infection circulating in Iran. Archives of virology. 2018 Jun;163(6):1479-88.
15. Poortahmasebi V, Poorebrahim M, Ghaziasadi A, Abazari MF, Mozhgani SH, Aleagha MN, Shahbazi F, Alavian SM. Analysis of antigenic and conformational changes in hepatitis B surface antigen (HBsAg) identified in iranian patients with chronic hepatitis B. Hepatitis Monthly. 2017 Sep 30;17(9).
16. Ghaziasadi A, Alavian SM, Norouzi M, Fazeli Z, Jazayeri SM. Mutational analysis of HBs Ag-positive mothers and their infected children despite immunoprophylaxis. Iranian Journal of Allergy Asthma and Immunology. 2013;12(4):352-60.
17. Ghaziasadi A, Ziaee M, Norouzi M, Malekzadeh R, Alavian SM, Saberfar E, Judaki MA, Ghamari S, Khedive A, Namazi A, Rahimnia R. The prevalence of hepatitis B virus surface antigen (HBsAg) variations and correlation with the clinical and serologic pictures in chronic carriers from Khorasan Province, North-East of Iran.

ارائه

• 23-25 Nov.2011.4^th international Tehran Hepatitis Congress.Gharazi Hall,Milad Hospital.Tehran,Iran.
• 23-25 Nov.2011.4^th international Tehran Hepatitis Congress.Gharazi Hall,Milad Hospital.Tehran,Iran
• 23-21 December 2011. 4^th Congress of Laboratory & Clinic.
• 26-29 April 2012.11^th International  Congress  of Immuonlogy and Allergy.Milad Tower.Tehran ,Iran
• 28-30 April 2012. 6^th Iranian Congress of Virology.
• 14-12 February 2015. 7^th International Congress of Laboratory and Clinical and 1th Conference of Clinical Virology.
• 26-28 October 2016. 4^th congress on Novel & Innovative Laboratory Technology. Tehran, Iran
• 6-8 september 2017 .7^th International Tehran Hepatitis Conferences. Tehran Iran.
• Application of Realtime PCR. May 2020 Mofid children Hospital.Tehran Iran.

مهارت

• Software and Web Based Knowledge including

Office software:  Bioedit- MEGA 4- ENDNOTE X 4- SPSS, Web page designing by Adobe Dreamweaver, Operating systems: Microsoft windows & Linux,  Scientific and General Database Advanced Search.

• Laboratory Knowledge including
• Basic cellular biology methods:

Cell Cultures, Fluorescent microscopy, Flow Cytometry, Electron microscopy (sample preparation)

• Basic Molecular Biology Methods:

PCR (Conventional PCR, RT-PCR, Real Time PCR),  ELISA, Molecular diagnostic, Western Blotting, Library preparation for NGS technique. 

• Applied Bioinformatics and Computational Biology Software

Biological database search, Sequence Alignment and Analysis Tools (BLAST, MEGA, EMBOSS sequence analysis package and DNA Star sequence analysis package), Protein structure prediction, Primer and probe designing and analysis tools (e.g. primer3, primerblast and oligo 6), Other NCBI utilities (e.g. sequin and ORF finder) and some other sequence assembly and analysis software’s applicable for gene manipulation (e.g. DNA baser and Chromas)

عضویت

• European Society of Clinical Microbiology and Infectious Diseases (ESCMID)
• Iranian Society for Virology
• Research Center for Clinical Virology at TUMS

زمینه علاقمندی

• vertical transmission of HBV and drug resistance in HBV and OBI infectious
• HIV infections and HCV infections 
• CMV infections
• Innate Immunity for defense of virology disease.
• Microbiology infection disease especially sepsis infections
• Virus-host interactions.
• Covid 19 infection.
• Real Time PCR development for diagnostic of Covid-19